C9orf72-KO

系統名

C57BL/6Smoc-C9orf72em1Smoc

SMOC番号

NM-KO-201246

維持形態

Sperm cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol

Synonyms

Denn， Dennd9， AI840585， 3110043O21Rik

NCBI ID

73205

MGI ID

1920455

Ensembl ID

ENSMUSG00000028300

Pubmed

Human Ortholog

C9orf72

説明

Exon 4-5 of C9orf72 gene was deleted to generate C9orf72 knockout mice.

病気の予測

Autoimmune Disease

表現型

MGI:6278552

参考文献

Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, Notarangelo LD, Eggan K, Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Sci Transl Med. 2016 Jul 13;8(347):347ra93

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細