Nexn-Flox

系統名

C57BL/6Smoc-Nexnem1(flox)Smoc

SMOC番号

TBD

維持形態

Developing

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遺伝子の概要

Gene Symbol
Nexn

Synonyms

NELIN， AA553326， 1110046H09Rik

NCBI ID

68810

MGI ID

1916060

Ensembl ID

ENSMUSG00000039103

Pubmed

Nexn

Human Ortholog

NEXN

説明

These mice carry loxP sites flanking target exons of Nexn gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nexn gene.

病気の予測

Dilated Cardiomyopathy 1Cc

表現型

MGI:6514900
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tnnt2-cre mice.

参考文献

Liu C, Spinozzi S, Chen JY, Fang X, Feng W, Perkins G, Cattaneo P, Guimaraes-Camboa N, Dalton ND, Peterson KL, Wu T, Ouyang K, Fu XD, Evans SM, Chen J, Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. Circulation. 2019 Jul 2;140(1):55-66

dilated cardiomyopathy 1CC

表現型

MGI:6514899
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with myl2-cre mice.

参考文献

Liu C, Spinozzi S, Chen JY, Fang X, Feng W, Perkins G, Cattaneo P, Guimaraes-Camboa N, Dalton ND, Peterson KL, Wu T, Ouyang K, Fu XD, Evans SM, Chen J, Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation. Circulation. 2019 Jul 2;140(1):55-66

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