Ppp1r13l-KO

系統名

C57BL/6Smoc-Ppp1r13lem1Smoc

SMOC番号

NM-KO-201327

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Ppp1r13l

Synonyms

wa3， IASPP， Nkip1， AV260376

NCBI ID

333654

MGI ID

3525053

Ensembl ID

ENSMUSG00000040734

Pubmed

Ppp1r13l

説明

Exon 4-7 of Ppp1r13l gene was deleted to generate Ppp1r13l knockout mice.

病気の予測

Arrhythmogenic Right Ventricular Cardiomyopathy

表現型

MGI:5910392

参考文献

Notari M, Hu Y, Sutendra G, Dedeic Z, Lu M, Dupays L, Yavari A, Carr CA, Zhong S, Opel A, Tinker A, Clarke K, Watkins H, Ferguson DJ, Kelsell DP, de Noronha S, Sheppard MN, Hollinshead M, Mohun TJ, Lu X, iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E973-81

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