hRTN4R

系統名

C57BL/6JSmo-Rtn4rtm1(hRTN4R)Smoc

SMOC番号

NM-HU-234373

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Rtn4r

説明

The endogenous mouse Rtn4r gene was replaced by human RTN4R gene.

表現型データ

image.png

Fig.1 Detection of RTN4R expression in frontal lobe and cerebellum by RT-PCR. 

Wild type: only one band at 421 bp with primers F1/R1(mRtn4r);

Homozygous: only one band at 190 bp with primers F2/R2(hRTN4R).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human RTN4R expression in hRTN4R knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.

Note. The anti-human RTN4R antibody cross-reacted with mouse RTN4R and humanized RTN4R. 

image.png

Fig.3 Detection of human RTN4R expression in hRTN4R knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous; PC, positive control, HepG2 cells.

Note. The anti-human RTN4R antibody cross-reacted with mouse RTN4R and humanized RTN4R. 


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