Lep-KO
系統名
B6;129S-Leptm1Smoc
SMOC番号
NM-KO-00034
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Lep
説明
病気の予測
表現型データ
Fig1. Body weight and Blood glucose monitoring of ob/ob mice.
Fig2. Evaluation of Oral glucose tolerance test (OGTT) of female ob/ob mice.
Abbr. HO, homozygous; WT, wild type. **, P ≤ 0.01.
Note. The tested ob/ob and C57BL/6 mice were 6 weeks old.
Fig3. Detection of insulin levels in serum by ELISA.
Abbr. Hom, homozygous; HE, heterozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old.
Fig4. H&E staining of the subcutaneous adipose tissue (SAT) in ob/ob mice.
Abbr. HO, homozygous; WT, wild type; WAT, white adipose tissue; BAT, brown adipose tissue.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 20.
Fig5. Representative pictures of pancreas in ob/ob mice.
These results suggested the inflammatory cell infiltration of the pancreas in ob/ob mice.
Abbr. HO, homozygous; WT, wild type.
Note. The tested ob/ob and C57BL/6 mice were 20 weeks old. Scale bar, 200 μm; magnification, × 10.
あなたも好きかも
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
詳細