KPC
系統名
C57BL/6Smoc-Trp53em4(R172H)Krasem4(LSL-G12D)Tg(Pdx1-cre)Smoc
SMOC番号
NM-KI-210096
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Trp53
Gene Symbol
Kras
Gene Symbol
pdx1
説明
病気の予測
表現型データ
Fig 1 The spontaneous pancreatic tumor of KPC mouse model with large volume, uneven surface and multiple nodular projections.
Fig 2 HE staining of pancreatic tumor from KPC mouse model.
The tumor cells from KPC mouse model demonstrated disorderly arranged pancreatic cells, irregular tissue structure, dilated pancreatic ducts, inflammatory cells infiltration and stromal fibrosis as was seen in pancreas adenocarcinoma.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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