Aplnr-2A-DreERT2
系統名
C57BL/6Smoc-Aplnrem1(2A-DreERT2)Smoc
SMOC番号
NM-KI-00132
維持形態
Embryo cryopreservation
遺伝子の概要
Gene Symbol
Aplnr
説明
A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.
応用分野：recombinase tool
*Literature published using this strain should indicate: Aplnr-2A-DreERT2 mice (Cat. NO. NM-KI-00132) were purchased from Shanghai Model Organisms Center, Inc..
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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