Zbtb46-2A-CreERT2

系統名

C57BL/6Smoc-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc

SMOC番号

NM-KI-18021

維持形態

Embryo cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Zbtb46

Synonyms

BZEL; Btbd4; 2610019F01Rik; 4933406L05Rik

NCBI ID

72147

MGI ID

1919397

Ensembl ID

ENSMUSG00000027583

Pubmed

Zbtb46

Human Ortholog

ZBTB46

説明

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
応用分野：Cre recombinase tool

表現型データ

image.png

Fig 1. Cre-mediated recombination in spleen of Zbtb46CreERT2/+; Rosa26tdTomato/+ mice.

image.png

Fig 2. Detection of tdTomato (red) in various tissues of Zbtb46CreERT2/+; Rosa26tdTomato/+. Expression tissues include: liver, salivary gland, pituitary gland, adrenal gland, kidney, pancreas, spleen, testis, thymus. A few cells expressed in cerebellum, spinal cord, heart, brown fat, small intestine, colon, muscle, skin. (6.5-8 weeks old, male) (For more detailed information please contact our technical advisor.) 

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細