Pax7-2A-DreERT2

系統名

C57BL/6Smoc-Pax7em1(2A-DreERT2)Smoc

SMOC番号

NM-KI-190124

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Pax7

Synonyms

Pax-7

NCBI ID

18509

MGI ID

97491

Ensembl ID

ENSMUSG00000028736

Pubmed

Pax7

Human Ortholog

PAX7

説明

A 2A-DreERT2 expression cassette was knocked into the Pax7 gene stop codon site.
応用分野：Dre tool mouse

表現型データ

NM-KI-190124 Pax7-2A-DreERT2-1.png

Fig. 1 DreERT2-mediated recombination in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse. 

RFP+ cells (red) were colocalized with GFP+ cells (green) in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse after tamoxifen treatment. However, the expression of RFP by induced dre with Pax7DreERT2/+ was less effective in the muscle. (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)

NM-KI-190124 Pax7-2A-DreERT2-2.png

Fig. 2: Detection of RFP in various tissues of Pax7DreERT2/+; Rosa26RFP/+ mice. (For more detailed information please contact our technical advisor.) (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)

出版物

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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