Th-IRES-CreERT2

系統名

C57BL/6Smoc-Them1(IRES-creER)Smoc

SMOC番号

NM-KI-200082

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Th

Synonyms

-

NCBI ID

21823

MGI ID

98735

Ensembl ID

ENSMUSG00000000214

Pubmed

Th

Human Ortholog

TH

説明

A IRES-creER expression cassette was knocked into the Th gene stop codon site.
応用分野：Cre recombinase tool, dopaminergic neurons in the brain

表現型データ

image.png

Fig1. Cre mediated recombination in brain of ThCreERT2/+;Rosa26tdTomato/+ mouse. (VTA: ventral tegmental area)

image.png

Fig2. Detection of tdTomato(red) in various tissues of ThCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: brain, islet. A few cells expressed in spinal cord, pituitary gland, small intestine, colon, skin, thymus and adrenal gland. Tissues that unexpressed include eye, heart, lung, liver, stomach, salivary glands, brown fat, kidney, spleen, muscle. Tamoxifen induction began at 49 days of age, with testing at 58 days. (For more detailed information please contact our technical advisor.) 

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