Scgb1a1-IRES-CreERT2

系統名

C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc

SMOC番号

NM-KI-200129

維持形態

Repository Live

PDFを取得

遺伝子の概要

Gene Symbol
Scgb1a1

Synonyms

UG; UGB; Utg; CC10; CC16; CCSP; PCB-BP

NCBI ID

22287

MGI ID

98919

Ensembl ID

ENSMUSG00000024653

Pubmed

Scgb1a1

Human Ortholog

SCGB1A1

説明

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.
応用分野：These mice express creERT2 recombinase from the Scgb1a1 locus (secretoglobin). This strain may useful for in the research of bronchiolar non-ciliated Clara cells.

表現型データ

NM-KI-200129 Scgb1a1-IRES-CreERT2-1.png

Fig.1 CreERT2-mediated recombination in the lung of  Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the bronchial and alveolar cells of  Scgb1a1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. 

NM-KI-200129 Scgb1a1-IRES-CreERT2-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Scgb1a1CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can be detected in the bronchial and alveolar cells after tamoxifen treatment. TdTomato expression can not be observed in the brain, pituitary gland, heart, liver, spleen, kidney, thymus, stomach, intestine, colon, submandibular gland, ovary, uterus, skin, muscle and brown fat. (For more detailed information please contact our technical advisor.)


あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細