Lgr5-2A-DreERT2

系統名

C57BL/6Smoc-Lgr5em1(2A-DreERT2)Smoc

SMOC番号

NM-KI-200178

維持形態

Sperm cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Lgr5

Synonyms

FEX; Gpr49

NCBI ID

14160

MGI ID

1341817

Ensembl ID

ENSMUSG00000020140

Pubmed

Lgr5

Human Ortholog

LGR5

説明

A 2A-DreERT2 expression cassette was knocked into the Lgr5 gene stop codon site.
応用分野：Dre recombinase tool

表現型データ

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Glutamine synthetase (GS, green) is expressed in a rim of hepatocytes surrounding hepatic veins. (Documented in the following reference.)


出版物

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細