hCD3EDG
系統名
C57BL/6-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
SMOC番号
NM-HU-220120
維持形態
Repository Live
遺伝子の概要
Gene Symbol
CD3E
Gene Symbol
CD3D
Gene Symbol
CD3G
説明
表現型データ
Fig 1. Expression detection of human CD3E/CD3D/CD3G by FACS in homozygous hCD3EDG mice.
Fig 2. Homozygous hCD3EDG mice were engrafted with MC38-hCLDN18.2 to eveluate the in vivo efficacy of anti-CD3×Claudin18.2 bispecific antibody in parallel with homozygous hCD3EDG mice.
Fig 3. Homozygous hCD3EDG mice were engrafted with MC38-hEpCAM to eveluate the AICD and irAE of OKT3 and anti-CD3×EpCAM bispecific antibody in vivo.
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