hHLA-A2.22

系統名

C57BL/6Smoc-H2-D1em1(hHLA-A2)Smoc

SMOC番号

NM-HU-204988

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
H2-D1

Gene Symbol
H2-D1

説明

The endogenous mice H2-D1 gene was replaced by human HLA-A2 gene.

表現型データ

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Fig1. Detection of HLA-A2 expression in spleen and intestine by RT-PCR. Wild type: only one band at 400 bp with primers F1/R1(mH2-D1);Heterozygous: one band at 400 bp with primers F1/R1(mH2-D1) and one band at 664 bp with primers F2/R2(hHLA-A2); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Expression of hHLA-A2 in blood, spleen, bone marrow and Liver in HLA-A2 KI mice. 

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Fig3. Immunophenotyping in HLA-A2 KI mice.

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Fig4. Immunophenotyping in Blood in HLA-A2 KI mice.

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Fig5. Immunophenotyping in Spleen in HLA-A2 KI mice.

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Fig6. Immunophenotyping in Bone Marrow in HLA-A2 KI mice.


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