hCD3EDG
系統名
C57BL/6-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
SMOC番号
NM-HU-220120
維持形態
Repository Live
遺伝子の概要
Gene Symbol
CD3E
Gene Symbol
CD3D
Gene Symbol
CD3G
説明
表現型データ
Fig 1. Expression detection of human CD3E/CD3D/CD3G by FACS in homozygous hCD3EDG mice.
Fig 2. Homozygous hCD3EDG mice were engrafted with MC38-hCLDN18.2 to eveluate the in vivo efficacy of anti-CD3×Claudin18.2 bispecific antibody in parallel with homozygous hCD3EDG mice.
Fig 3. Homozygous hCD3EDG mice were engrafted with MC38-hEpCAM to eveluate the AICD and irAE of OKT3 and anti-CD3×EpCAM bispecific antibody in vivo.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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