hSIRPA(2)

系統名

C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc

SMOC番号

NM-HU-18015

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Sirpa

説明

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.
応用分野:Immunotherapy,drug screening

表現型データ

sirpa 流式.png

Figure 1. Detection of SIRPA expression in peripheral blood cells of humanized SIRPA mice.The FACS results of peripheral blood cells showed that the active expression of humanized SIRPA was detected in B cells and macrophage cells collected from heterozygous humanized SIRPA mice.(Completed in collaboration with CrownBio).


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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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