hTLR9

系統名

C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc

SMOC番号

NM-HU-18016

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Tlr9

Synonyms

NCBI ID

81897

MGI ID

1932389

Ensembl ID

ENSMUSG00000045322

Pubmed

Tlr9

Human Ortholog

TLR9

説明

This TLR9 humanized mouse model was established by replacing the mouse Tlr9 gene exon2 with the human TLR9 corresponding sequence by homologous recombination.

応用分野：drug screening

表現型データ

image.png

Fig.1 Detection of hTLR9 and mTlr9 expression in Peripheral blood in WT C57BL/6 and HO hTLR9 KI mice. 

image.pngFig.2 Detection of hTLR9 and mTlr9 expression in Spleen in WT C57BL/6 and HO hTLR9 KI mice.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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