hIl5

系統名

C57BL/6Smoc-Il5tm3(hIL5)Smoc

SMOC番号

NM-HU-190001

維持形態

Embryo cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
IL5

Synonyms

Il-5

NCBI ID

16191

MGI ID

96557

Ensembl ID

ENSMUSG00000036117

Pubmed

IL5

Human Ortholog

IL5

説明

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.
応用分野：Immune-related

表現型データ

image.png

Fig1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL5-Hu.png

Fig 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

IL5-Mu.png

Fig 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細