hCD40/h4-1BB(2)
系統名
C57BL/6Smoc-Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
SMOC番号
NM-HU-200256
維持形態
Repository Live
遺伝子の概要
Gene Symbol
CD40
Gene Symbol
Tnfrsf9
説明
表現型データ
Fig1. In vivo validation of double humanized CD40&4-1BB mice. Double humanized mice were inoculated with B16F10 cells, and randomly assigned to different groups (n=6) when the tumor grew to a volume of 80 mm3. A combinatorial treatment of anti-CD40 and anti-4-1BB inhibited tumor growth (top) without affecting the animal body weight (Bottom).
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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