hIL2
系統名
C57BL/6Smoc-Il2tm3(hIL2)Smoc
SMOC番号
NM-HU-190048
維持形態
Embryo cryopreservation
遺伝子の概要
Gene Symbol
IL2
説明
表現型データ
Fig1. Detection of IL2 expression by RT-PCR.
Wild type: only one band at 255 bp with primers F2/R2(mIl2); Homozygous: only one band at 320 bp with primers F1/R1(hIL2).
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Expression of human IL2 in the Serum of IL2-HU heterozygous mice is detected by ELISA.
Fig3. Expression of murine IL2 in the Serum of IL2-HU heterozygous mice and is detected by ELISA.
Fig4. Splenocytes from humanized IL2 mice were analyzed by flow cytometry after activation.
hIL2+ (but not mIL2+) cells were detectable in the homozygous hPD-L2 mice.
あなたも好きかも
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
詳細