hCXCR6

系統名

C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc

SMOC番号

NM-HU-215001

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Cxcr6

Synonyms

BONZO; STRL33; BB217514

NCBI ID

80901

MGI ID

1934582

Ensembl ID

ENSMUSG00000048521

Pubmed

Cxcr6

Human Ortholog

CXCR6

説明

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

表現型データ

image.png

Fig1. Detection of CXCR6 expression in spleen  by RT-PCR. Wild type: only one band at 423 bp with primers F1/R1(mCxcr6);Homozygous: only one band at 206 bp with primers F2/R2(hCXCR6); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hCXCR6 expression on NKT cells in spleen in hCXCR6 KI mice.

image.png


Fig3. Detection of hCXCR6 expression on splenocyte-derived activated T cells in hCXCR6 KI mice. 

Note. Splenocytes from C57BL/6 and homozygous hCXCR6 mice were stimulated with anti-mCD3 and anti-mCD28 in vitro. 




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