hCD44

系統名

C57BL/6Smoc-Cd44em(hCD44)Smoc

SMOC番号

NM-HU-215003

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Cxcr5

説明

The endogenous mice Cd44 gene was replaced by human CD44 gene.

表現型データ

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Fig1. Detection of CD44 expression in spleen and lung by RT-PCR. Wild type: only one band at 213 bp with primers F1/R1(mCd44);Heterozygous: one band at 213 bp with primers F1/R1(mCd44) and one band at 442 bp with primers F2/R2(hCD44); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Expression characterization of hCD44 on MOLM-16 cell line.

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Fig3. Expression characterization of hCD44 in Blood in hCD44 KI mice.

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Fig4. Expression characterization of hCD44 in Spleen in hCD44 KI mice.

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Fig5. Expression characterization of hCD44 in Bone Marrow in hCD44 KI mice.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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