hIL10RA

系統名

C57BL/6Smoc-Il10ratm1(hIL10RA)Smoc

SMOC番号

NM-HU-215072

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Il10ra

説明

The endogenous mouse Il10ra gene was replaced by human IL10RA gene.

表現型データ

image.png

Fig1. Detection of IL10RA expression in spleen by RT-PCR. 

Wild type: only one band at 272 bp with primers F1/R1(mIl10ra);

Homozygous: only one band at 278 bp with primers F2/R2(hIL10RA).

Abbr. M, DNA marker; HO, homozygous;  WT, wild type.

image.png

Fig2. Detection of human IL10RA expression on macrophages in peritoneal washes in hIL10RA KI mice.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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