hIL5/hIL5R(3)

系統名

C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc

SMOC番号

NM-HU-220011

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
IL5

Synonyms

Il-5

NCBI ID

16191

MGI ID

96557

Ensembl ID

ENSMUSG00000036117

Pubmed

IL5

Human Ortholog

IL5

Gene Symbol
IL5Ra

Synonyms

Il5r; CD125; CDw125

NCBI ID

16192

MGI ID

96558

Ensembl ID

ENSMUSG00000005364

Pubmed

IL5Ra

Human Ortholog

IL5RA

説明

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.
応用分野：Immunotherapy,cancer research,drug screening

表現型データ

image.png

Fig1. Expression of hIL5R on Bone marrow-derived eosinophils in hIL5/hIL5R(3) dKI mice.

Note: Eosinophils were derived from bone marrow cells through culture with rmSCF, rmFLT-3L, and rmlL-5.

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