hPTGDR2

系統名

C57BL/6Smoc-Ptgdr2em1(hPTGDR2)Smoc

SMOC番号

NM-HU-225033

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Ptgdr2

Synonyms

Crth2; Gpr44; Grp45

NCBI ID

14764

MGI ID

1330275

Ensembl ID

ENSMUSG00000034117

Pubmed

Ptgdr2

Human Ortholog

PTGDR2

説明

The endogenous mouse Ptgdr2 gene was replaced by human PTGDR2 gene.

表現型データ

image.png

Fig1. Detection of PTGDR2 expression in brain, stomach, colon and ovary by RT-PCR. 

Wild type: only one band at 227 bp with primers F1/R1(mPtgdr2);

Homozygous: only one band at 263 bp with primers F2/R2(hPTGDR2); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of PTGDR2 expression on eosinophils in spleen in C57BL/6 and hPTGDR2 KI mice.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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