hHER3(2)
系統名
C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
SMOC番号
NM-HU-225068
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Erbb3
説明
The endogenous mouse Erbb3 gene was replaced by human ERBB3 gene.
表現型データ
Fig.1 Detection of ERBB3 expression in colon by RT-PCR.
Wild type: only one band at 343 bp with primers F1/R1(mErbb3);
Homozygous: only one band at 305 bp with primers F2/R2(hERBB3).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human hHER3 expression in hHER3(2) knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, homozygous; PC, positive control, MC38-hHER3 cells.
Note. The anti-human hHER3 antibody cross-reacted with mouse hHER3 and humanized hHER3.
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