hCD40(BALB/c)

系統名

BALB/cAnSmoc-Cd40em1(hCD40)/Smoc

SMOC番号

NM-HU-2000047

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
CD40

Synonyms

IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936

NCBI ID

21939

MGI ID

88336

Ensembl ID

ENSMUSG00000017652

Pubmed

CD40

Human Ortholog

CD40

説明

The endogenous mouse Cd40 gene was replaced by human CD40 gene.
応用分野：Immunotherapy,drug screening

表現型データ

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Fig1. Analysis of hCD40 expression in PBMC in the hCD40 mice by FACS. hCD40 was expressed on B cells in PB.

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Fig2. Analysis of hCD40 expression on splenic B cells by FACS. hCD40 was expressed on the B cells in the spleen.

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Fig3. Analysis of human CD40 expression on splenic DCs and macrophages by FACS . The homozygous KI mouse expresses human CD40 on DCs and macrophages.（Provided by CrownBio）


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