hIL2RB

系統名

C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc

SMOC番号

NM-HU-2000055

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
IL2RB

Synonyms

p70; CD122; IL15Rbeta; Il-2Rbeta; IL-15Rbeta; Il-2/15Rbeta

NCBI ID

16185

MGI ID

96550

Ensembl ID

ENSMUSG00000068227

Pubmed

IL2RB

Human Ortholog

IL2RB

説明

The endogenous mouse Il2rb gene was replaced by human IL2RB gene.
応用分野：Cytokine humanization model；drug screening

表現型データ

NM-HU-2000055 hIL2RB.png

Fig1. Analysis of IL2RB gene expression in the liver by RT-PCR.

Mouse Il2rb mRNA was detectable by P1/2(511bp), human IL2RB mRNA was detectable by P1/3(513bp), 

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human IL2RB and mouse Il2rb in the liver.

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