hCD24

系統名

C57BL/6Smoc-Cd24atm1(hCD24)/Smoc

SMOC番号

NM-HU-2000060

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
CD24a

Synonyms

HSA; Cd24; Ly-52; nectadrin

NCBI ID

12484

MGI ID

88323

Ensembl ID

ENSMUSG00000047139

Pubmed

CD24a

Human Ortholog

CD24A

説明

The endogenous mouse Cd24a gene was replaced by human CD24 gene. While hCD24(2)(Stock No.NM-HU-215025) mice function similarly to hCD24 mice, for more detailed information please contact our technical advisor.
応用分野：Immunotherapy,drug screening

表現型データ

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Fig1. Detection of CD24 expression in spleen and brain by RT-PCR. Wild type: only one band at 175 bp with primers F1/R1(mCd24);Homozygous: only one band at 202 bp with primers F2/R2(hCD24); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Detection of hCD24 expression on B cells and T cells in blood in hCD24 KI mice.

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Fig3. Detection of hCD24 expression on macrophages, neutrophils and DCs in blood in hCD24 KI mice.

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Fig4. Detection of hCD24 expression on B cells and T cells in spleen in hCD24 KI mice.

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Fig5. Detection of hCD24 expression on macrophages, neutrophils and DCs in spleen in hCD24 KI mice.

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Fig6. Detection of hCD24 expression on RBC (red blood cells)  in hCD24 KI mice.

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