hIL1RL1
系統名
C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
SMOC番号
NM-HU-2000067
維持形態
Sperm cryopreservation
遺伝子の概要
Gene Symbol
Il1rl1
説明
The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.
表現型データ
Fig1. Detection of IL1RL1 expression in large intestine by RT-PCR in hIL1RL1 mice.
Wild type: only one band at 296 bp with primers F1/R1(mIl1rl1);
Homoygous: only one band at 367 bp with primers F2/R2(hIL1RL1);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig2. Expression of hIL1RL1 on CD4+ T cells in spleen in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).
Fig3. Expression of hIL1RL1 on mast cells in bone marrow in hIL1RL1/hIL4/hIL4R mice (NM-HU-232112), which were generated by crossing hIL4/hIL4R (NM-HU-2000106) with hIL1RL1 (NM-HU-2000067).
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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