hHBB

系統名

C57BL/6Smoc-Hbb-bt&Hbb-bstm1(hHBB)/Smoc

SMOC番号

NM-HU-2000080

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Hbb-bt

Synonyms

Beta-t

NCBI ID

101488143

MGI ID

5474850

Ensembl ID

ENSMUSG00000073940

Pubmed

Hbb-bt

Human Ortholog

HBB-BT

Gene Symbol
Hbb-bs

Synonyms

Hbbt1; Hbbt2; Beta-s

NCBI ID

100503605

MGI ID

5474852

Ensembl ID

ENSMUSG00000052305

Pubmed

Hbb-bs

Human Ortholog

HBB-BS

説明

The endogenous mouse Hbb-bt and Hbb-bs gene was replaced by human HBB gene.
応用分野：Thalassemia research；drug screening

表現型データ

image.png

Fig.1 Detection of HBB expression in spleen by RT-PCR (7-8wks, male). 

Wild type: one band at 139 bp with primers F1/R1 (mHbb-bt/Hbb-bs) and one band at 178 bp with primers F2/R2 (mHbb-bs/Hbb-bt);

Homozygous: only one band at 162 bp with primers F3/R3 (hHBB).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

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