hCD20(2)

系統名

C57BL/6Smoc-Ms4a1tm2 (hCD20)Smoc

SMOC番号

NM-HU-200114

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Ms4a1

Synonyms

Cd20; Ly-44; Ms4a2; AA960661

NCBI ID

12482

MGI ID

88321

Ensembl ID

ENSMUSG00000024673

Pubmed

Ms4a1

Human Ortholog

MS4A1

説明

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.
応用分野：Immune-related; drug screening

表現型データ

71660ff7f7c1b6108cefd5fb18be7a1.png

Fig1. Detection of hCD20 expression on mCD19+ B cells in blood in hCD20 knockin mice.

NM-HU-200114-fig2.png

Fig2. Rituximab can bind to lymphocytes of hCD20 knockin mice.

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