hCTLA-4/hCD28(BALB/c)

系統名

BALB/cAnSmoc-Ctla4em1(hCTLA4)Cd28em1(hCD28)Smoc

SMOC番号

NM-HU-200226

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
CD28

Synonyms

NCBI ID

12487

MGI ID

88327

Ensembl ID

ENSMUSG00000026012

Pubmed

CD28

Human Ortholog

CD28

Gene Symbol
CTLA4

Synonyms

Cd152; Ly-56; Ctla-4

NCBI ID

12477

MGI ID

88556

Ensembl ID

ENSMUSG00000026011

Pubmed

CTLA4

Human Ortholog

CTLA4

説明

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.
応用分野：Immunotherapy

表現型データ

2.png

Fig1. Analysis of human CTLA4(hCD152) expression in the spleen by FACS . The homozygous KI mouse expresses human CTLA4 on T cells.

3.png

Fig2. Analysis of human CD28 expression in the spleen by FACS . The homozygous KI mouse expresses human CD28 on T cells.

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