hTIGIT(3)

系統名

C57BL/6Smoc-Tigittm3(hTIGIT)Smoc

SMOC番号

NM-HU-200244

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
TIGIT

Synonyms

Vstm3

NCBI ID

100043314

MGI ID

3642260

Ensembl ID

ENSMUSG00000071552

Pubmed

TIGIT

Human Ortholog

TIGIT

説明

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

表現型データ

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Fig1. Strain specific hTIGIT expression analysis in homozygouse hTIGIT mice by flow cytometry. T cells of PBMC were collected from WT and homozygouse hTIGIT mice, and analyzed by flow cytometry with species-specific anti-hTIGIT antibody. hTIGIT was expressed in T cells of homozygouse hTIGIT mice.

2.png

Fig2. Strain specific hTIGIT expression analysis in homozygouse hTIGIT mice by flow cytometry. Spleen derived T cells were collected from WT and homozygouse hTIGIT mice, and analyzed by flow cytometry with species-specific anti-hTIGIT antibody. hTIGIT was detectable in a subset of T cells in homozygouse hTIGIT mice.

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