hOX40(2)

系統名

C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4) Smoc

SMOC番号

NM-HU-00078

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Tnfrsf4

Synonyms

Ox40; ACT35; CD134; Ly-70; Txgp1; TXGP1L

NCBI ID

22163

MGI ID

104512

Ensembl ID

ENSMUSG00000029075

Pubmed

Tnfrsf4

Human Ortholog

TNFRSF4

説明

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.
応用分野：cancer research,Immunotherapy,drug screening

表現型データ

image.png

Fig1. Detection of hOX40 expression in splenocyte-derived activated T cells in hOX40 KI mice.

Note. Splenocytes from C57BL/6 and homozygous hOX40 mice were stimulated with ConA in vitro. 

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