hHLA-A11

系統名

C57BL/6Smoc-H2-K1tm1(hHLA-A11)Smoc

SMOC番号

NM-HU-204987

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
H2-K1

Synonyms

K-f; H-2K; H2-K; H2-D1; H2-K_p; H-2K(d)

NCBI ID

14972

MGI ID

95904

Ensembl ID

ENSMUSG00000061232

Pubmed

H2-K1

Human Ortholog

HLA-A，HLA-E，HLA-F

説明

The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.

表現型データ

image.png

Fig1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.

Wild type: only one band at 369 bp with primers F1/R1(mH2-k1);

Heterozygous: one band at 369 bp with primers F1/R1(mH2-k1) and one band at 215 bp with primers F2/R2(hHLA-A11).

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of HLA-A11 expression in blood in HLA-A11 KI mice.

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