hF12

系統名

C57BL/6Smoc-F12tm1(hF12)/Smoc

SMOC番号

NM-HU-210017

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
F12

Synonyms

HAF; FXII

NCBI ID

58992

MGI ID

1891012

Ensembl ID

ENSMUSG00000021492

Pubmed

F12

Human Ortholog

F12

説明

The endogenous mice F12 gene was replaced by human F12 gene.
応用分野：drug screening

表現型データ

image.png

Fig1. Detection of F12 expression in liver by RT-PCR. 

Wild type: only one band at 318 bp with primers F1/R1(mF12);

Homozygous: only one band at 274 bp with primers F2/R2(hF12); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3). 

Abbr. HO, homozygous; WT, wild type.  

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