hF12

系統名

C57BL/6Smoc-F12tm1(hF12)/Smoc

SMOC番号

NM-HU-210017

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
F12

説明

The endogenous mice F12 gene was replaced by human F12 gene.
応用分野:drug screening

表現型データ

image.png

Fig1. Detection of F12 expression in liver by RT-PCR. 

Wild type: only one band at 318 bp with primers F1/R1(mF12);

Homozygous: only one band at 274 bp with primers F2/R2(hF12); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human F12 (A) and mouse F12 (B) expression in serum by ELISA (male, 8-11wks, n=2). 

Abbr. HO, homozygous; WT, wild type.

image.png

Fig.3 Detection of hF12 expression in serum by ELISA (male, n=3). 

Abbr. HO, homozygous; WT, wild type.  


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