CAG-hACE2-IRES-Luc-Tg
系統名
C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
SMOC番号
NM-TG-200002
維持形態
Repository Live
遺伝子の概要
Gene Symbol
説明
表現型データ
Figure 1. Luciferase expression of the CAG-hACE2-IRES-Luciferase transgenic mice.
Figure 2. Western blot analysis of ACE2 protein from the CAG-hACE2-IRES-Luciferase transgenic mice.
Figure 3. Virus titers in the lungs of hACE2 Tg mice after SARS-CoV-2 infection. Groups of hACE2 Tg mice and wild type mice were inoculated with the same dose of SARS-CoV-2, the result shows that hACE2 Tg mice were highly susceptible to SARS-CoV-2 infection.
Figure 4. Body weight change in hACE2 Tg mice after drug treatment.
Figure 5. The viral load in the lung tissues of hACE2 Tg mice after drug treatment.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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