Prkn-KO

系統名

C57BL/6Smoc-Prknem1Smoc

SMOC番号

NM-KO-190335

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol

Synonyms

Park2 Parkin PRKN

NCBI ID

50873

MGI ID

1355296

Ensembl ID

ENSMUSG00000023826

Pubmed

Human Ortholog

PRKN

説明

Prkn-KO mice (Stock No.NM-KO-190335）carry a knockout allele derived from the targeted deletion of exon 3. While Prkn-KO(2) mice (Stock No.NM-KO-191005）mice carrying the exon 4 deletion.
応用分野：Immune-related

病気の予測

Parkinson's Disease 2

表現型

MGI:2678248

参考文献

Itier JM, Ibanez P, Mena MA, Abbas N, Cohen-Salmon C, Bohme GA, Laville M, Pratt J, Corti O, Pradier L, Ret G, Joubert C, Periquet M, Araujo F, Negroni J, Casarejos MJ, Canals S, Solano R, Serrano A, Gallego E, Sanchez M, Denefle P, Benavides J, Tremp G,Rooney TA, Brice A, Garcia de Yebenes J, Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet. 2003 Sep 15;12(18):2277-91

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