Akt1-KO

系統名

C57BL/6Smoc-Akt1em1Smoc

SMOC番号

NM-KO-190741

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Akt1

Synonyms

Akt， PKB， Rac， LTR-akt， PKB/Akt， PKBalpha

NCBI ID

11651

MGI ID

87986

Ensembl ID

ENSMUSG00000001729

Pubmed

Akt1

Human Ortholog

AKT1

説明

Exon 2 of Akt1 gene was deleted to generate Akt1 knockout mice.
応用分野：Pro-Inflammatory, Anti-Apoptotic and Stress Responses related.

病気の予測

Schizophrenia

表現型

MGI:2674288

参考文献

Emamian ES, Hall D, Birnbaum MJ, Karayiorgou M, Gogos JA, Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet. 2004 Feb;36(2):131-7

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