Plau-KO

系統名

C57BL/6Smoc-Plauem1Smoc

SMOC番号

NM-KO-190855

維持形態

Sperm cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Plau

Synonyms

uPA， u-PA

NCBI ID

18792

MGI ID

97611

Ensembl ID

ENSMUSG00000021822

Pubmed

Plau

Human Ortholog

PLAU

説明

Exon 3-4 of Plau gene was deleted to generate Plau knockout mice.
応用分野：Alzheimer's Disease ,Beta-Amyloid Generation, Oligomerization, Clearance & Degradation, immune system,

病気の予測

Alzheimer's Disease

表現型

MGI:2662716

参考文献

Ertekin-Taner N, Ronald J, Feuk L, Prince J, Tucker M, Younkin L, Hella M, Jain S, Hackett A, Scanlin L, Kelly J, Kihiko-Ehman M, Neltner M, Hersh L, Kindy M, Markesbery W, Hutton M, de Andrade M, Petersen RC, Graff-Radford N, Estus S, Brookes AJ, Younkin SG, Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene. Hum Mol Genet. 2005 Feb 1;14(3):447-60

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

詳細