Ctnnb1-Flox

MGI:5432226
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Pten-Flox(NM-CKO-18004) and CYP19A1-cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20

MGI:4941746
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Pten-Flox(NM-CKO-18004) and Amhr2-Cre mice.

Boyer A, Paquet M, Lague MN, Hermo L, Boerboom D, Dysregulation of WNT/CTNNB1 and PI3K/AKT signaling in testicular stromal cells causes granulosa cell tumor of the testis. Carcinogenesis. 2009 May;30(5):869-78

MGI:3836579
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Pbsn-cre mice.

Pearson HB, Phesse TJ, Clarke AR, K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse. Cancer Res. 2009 Jan 1;69(1):94-101

MGI:5790500
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Kras-LSL-G12D(NM-KI-190003) and Upk2-cre mice.

Ahmad I, Patel R, Liu Y, Singh LB, Taketo MM, Wu XR, Leung HY, Sansom OJ, Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis. Cell Death Dis. 2011;2:e124

MGI:5432224
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Kras-LSL-G12D(NM-KI-190003) and CYP19A1-cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20

MGI:5432231
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Kras-LSL-G12D(NM-KI-190003) and Amhr2-Cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20

MGI:5141741
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Fgfr3-Flox(NM-CKO-2101148) and Upk2-cre mice.

Ahmad I, Singh LB, Foth M, Morris CA, Taketo MM, Wu XR, Leung HY, Sansom OJ, Iwata T, K-Ras and {beta}-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder. Dis Model Mech. 2011 Jul-Aug;4(4):548-55

MGI:5432223
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with CYP19A1-cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20

MGI:5432232
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Ctnnb1-Flox(NM-CKO-200154) and Amhr2-Cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20

MGI:3706580
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with CMV-cre mice.

Schmidt-Ullrich R, Aebischer T, Hulsken J, Birchmeier W, Klemm U, Scheidereit C, Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development. 2001 Oct;128(19):3843-53

MGI:4418449
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Cdkn2a-Flox(2)(NM-CKO-200151)，Pten-Flox(NM-CKO-18004) and Tyr-cre/ERT2 mice.

Held MA, Curley DP, Dankort D, McMahon M, Muthusamy V, Bosenberg MW, Characterization of melanoma cells capable of propagating tumors from a single cell. Cancer Res. 2010 Jan 1;70(1):388-97

MGI:5790498
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Cdkn1a-Flox(NM-CKO-200033) and Upk2-cre mice.

Ahmad I, Patel R, Liu Y, Singh LB, Taketo MM, Wu XR, Leung HY, Sansom OJ, Ras mutation cooperates with beta-catenin activation to drive bladder tumourigenesis. Cell Death Dis. 2011;2:e124

MGI:5508218
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Bmpr1a-Flox(NM-CKO-2100038) and KRT14-cre mice.

Wend P, Fang L, Zhu Q, Schipper JH, Loddenkemper C, Kosel F, Brinkmann V, Eckert K, Hindersin S, Holland JD, Lehr S, Kahn M, Ziebold U, Birchmeier W, Wnt/beta-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours. EMBO J. 2013 Jul 17;32(14):1977-89

MGI:5432228
Note：The expected phenotype(s) may be observed in the above-mentioned mice that bred with Amhr2-Cre mice.

Richards JS, Fan HY, Liu Z, Tsoi M, Lague MN, Boyer A, Boerboom D, Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis. Oncogene. 2012 Mar 22;31(12):1504-20