Pink1-KO

系統名

C57BL/6Smoc-Pink1em1Smoc

SMOC番号

NM-KO-191011

維持形態

Sperm cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Pink1

Synonyms

BRPK; AU042772; AW557854; mFLJ00387; 1190006F07Rik

NCBI ID

68943

MGI ID

1916193

Ensembl ID

ENSMUSG00000028756

Pubmed

Pink1

Human Ortholog

PINK1

説明

Exon 2-4 of Pink1 gene was deleted to generate Pink1 knockout mice.
応用分野：mitochondrial homeostasis, autosomal recessive early-onset Parkinson disease

病気の予測

Parkinson's Disease 6

表現型

MGI:3716639

参考文献

Kitada T, Pisani A, Porter DR, Yamaguchi H, Tscherter A, Martella G, Bonsi P, Zhang C, Pothos EN, Shen J, From the Cover: Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11441-6

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細