Cldn16-KO

系統名

C57BL/6Smoc-Cldn16em1Smoc

SMOC番号

NM-KO-200632

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Cldn16

Synonyms

PCLN1， claudin-16

NCBI ID

114141

MGI ID

2148742

Ensembl ID

ENSMUSG00000038148

Pubmed

Cldn16

Human Ortholog

CLDN16

説明

Exon 2 of Cldn16 gene was deleted to generate Cldn16 knockout mice.
応用分野：Sertoli-Sertoli cell junction dynamics and cell junction organization related research

病気の予測

Renal Hypomagnesemia 3

表現型

MGI:4453304

参考文献

Will C, Breiderhoff T, Thumfart J, Stuiver M, Kopplin K, Sommer K, Gunzel D, Querfeld U, Meij IC, Shan Q, Bleich M, Willnow TE, Muller D, Targeted deletion of murine Cldn16 identifies extra- and intrarenal compensatory mechanisms of Ca2+ and Mg2+ wasting. Am J Physiol Renal Physiol. 2010 May;298(5):F1152-61

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