Dmpk-KO

系統名

C57BL/6Smoc-Dmpkem1Smoc

SMOC番号

NM-KO-200635

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Dmpk

Synonyms

DM; DMK; Dm15; MDPK; MT-PK

NCBI ID

13400

MGI ID

94906

Ensembl ID

ENSMUSG00000030409

Pubmed

Dmpk

Human Ortholog

DMPK

説明

Exon 1-7 of Dmpk gene was deleted to generate Dmpk knockout mice.
応用分野：Cardiac conduction and G protein signal transduction RAC1 in cellular processes

病気の予測

Myotonic Dystrophy Type 1

表現型

MGI:3613697

参考文献

Reddy S, Smith DB, Rich MM, Leferovich JM, Reilly P, Davis BM, Tran K, Rayburn H, Bronson R, Cros D, Balice-Gordon RJ, Housman D, Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy [see comments]. Nat Genet. 1996 Jul;13(3):325-35

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