Sh2d1a-KO

系統名

C57BL/6Smoc-Sh2d1aem1Smoc

SMOC番号

NM-KO-200730

維持形態

Embryo cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Sh2d1a

Synonyms

SAP， Gm686

NCBI ID

20400

MGI ID

1328352

Ensembl ID

ENSMUSG00000005696

Pubmed

Sh2d1a

Human Ortholog

SH2D1A

説明

Exon 2 of Sh2d1a gene was deleted to generate Sh2d1a knockout mice.

病気の予測

X-Linked Lymphoproliferative Syndrome 1

表現型

MGI:3036915

参考文献

Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL, Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7449-54

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細