Cdh1-2A-DreERT2

系統名

C57BL/6JSmo-Cdh1em3(2A-DreERT2)Smoc

SMOC番号

NM-KI-190031

維持形態

Sperm cryopreservation

PDFを取得

遺伝子の概要

Gene Symbol
Cdh1

Synonyms

Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649

NCBI ID

12550

MGI ID

88354

Ensembl ID

ENSMUSG00000000303

Pubmed

Cdh1

Human Ortholog

CDH1

説明

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.
応用分野：Dre recombinase tool

表現型データ

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Cdh1 gene encodes E-cadherin(E-CAD), a calcium-dependent adhesion  molecule that expressed primarily in epithelial cells. (Documented in the following reference.)


出版物 1piece

1. A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
Published year：2021-02-09 References：CELL STEM CELL

展开

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細

Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

詳細

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

詳細