B2m-KO

系統名

C57BL/6Smoc-B2mem3Smoc

SMOC番号

NM-KO-18021

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
B2M

説明

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.
応用分野:immune system

表現型データ

b2m流式.png

Fig1 . There are few CD8+ cytotoxic T-cells and increase in CD4+ T-cells in B2M knockout mice. Immune responses involving CD8+T-cells are severely deficient providing a model to assess the role of CD8+ cells and class I MHC in various experimental systems. 



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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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