B2m-KO(NMG)

系統名

NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc

SMOC番号

NM-NSG-002

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
B2m

説明

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

応用分野:immunodeficiency,immune system,transplantation research

表現型データ

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Fig1.Detection of MHCII and B2m expression in spleen in B2m-KO(NMG) mice by RT-PCR. 

Abbr. M, DNA marker

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Fig2. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice.

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Fig 3. Body weight growth curve of huPBMC-B2m-KO(NMG) mice.

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Fig 4. Survival rate of huPBMC-B2m-KO(NMG) mice.

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Fig 5. GvHD scores of huPBMC-B2m-KO(NMG) mice.

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Fig 6. Percentage of hCD45-positive cells of huPBMC-B2m-KO(NMG) mice.

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Fig 7. Flow analysis of peripheral blood lymphocyte subpopulations in the huPBMC-B2m-KO(NMG) mice.


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