hIL4-Tg(NMG)
系統名
NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
SMOC番号
NM-KI-215004
維持形態
Embryo cryopreservation
遺伝子の概要
Gene Symbol
IL4
説明
These transgenic mice carry humanized IL4.
表現型データ
Fig1. Detection of hIL4 expression by RT-PCR.
Heterozygous: one band at 223 bp with primers F1/R1(hIL4);
Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Fig 2. Detection of hIL4 expression in serum by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.、
Fig 3. Body weight growth curve of huPBMC-M-NSG-hIL4 mice.
Fig 4. Survival rate of huPBMC-M-NSG-hIL4 mice.
Fig 5. GvHD scores of huPBMC-M-NSG-hIL4 mice.
Fig 6. Percentage of hCD45-positive cells in peripheral blood of huPBMC-M-NSG-hIL4 mice.
Fig 7. Flow analysis of peripheral blood lymphocyte subpopulations in the huPBMC-M-NSG-hIL4 model. Human PBMCs (1E7) were injected intravenously into hIL4-Tg(M-NSG) mice (female, 6-8 weeks old, n=10). Blood from mice at different time points after implantation of human PBMCs was taken for flow cytometric analysis.
あなたも好きかも
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
詳細